While I explicitly teach prefixes through our vocabulary program, my 5th graders still need more practice. I created these 30 prefix puzzles to use during the ‘Word Work’ section of literacy centers. I choose 5-6 puzzles for students to practice each week.Included in this resource…Notes to the Teacher40 Prefix Puzzles (Anti-Auto-, Bi-, Co-, Centi-, Deca-, Dis-, En-, Ex-, Fore-, In-/im-, Inter-, Kilo-, Milli-, Mis-, Multi-, Non-, Oct-, Pre-, Pro-, Quad-, Re-, Se-, Semi-, Sub-, Super-, Tele-, Tri-