***** 5-STAR Premium S.T.E.M. Lesson SALE $19.99 Limited Time Offer. 50-PAGES Which is Bigger? Which is Smaller? Cells & Macromolecules Distance Learning. Macromolecules are large molecules composed of thousands of covalently connected atoms. Carbohydrates, lipids, proteins, and nucleic acids are all macromolecules. Macromolecules are formed by many monomers linking together, forming a polymer. Carbohydrates are composed of carbon, oxygen, and hydrogen. Students are challenged to constr